CMB
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Cell and Molecular
Biology (CMB) is a degree-granting unit within the
Molecular Biosciences cluster, which
also includes:
•
Biochemistry and Molecular Biophysics (BMB)
• Committee on Developmental
Biology (CDB)
• Committee
on Genetics, Genomics & Systems Biology (GGSB)
• Human Genetics.
The academic units of the cluster share a core
curriculum and a common admissions process.
The goal of the doctoral program in Cell and
Molecular Biology is to foster advanced scholarship and research
in the combined areas of cell biology, genetics, and molecular biology.
Students are introduced to a broad spectrum of experimental rationales
and technical approaches and typically learn several in depth. Skills
in genetic analysis include transgenic, reverse genetic, and genomic
analysis, as well as molecular analysis of genes and gene products.
Skills in structural analysis include the use of advanced optical
and electron microscopy, including EM tomography, atomic force microscopy,
and dynamic in vivo imaging. Students learn to identify the model
organisms and the appropriate tools and techniques that will allow
them to answer their scientific questions in the most effective
way. Among the model organisms in which training is available are
eukaryotic and prokaryotic viruses, diverse bacteria including cyanobacteria,
Tetrahymena, Saccharomyces and other yeasts, Chlamydomonas, Drosophila,
Caenorhabditis, Arabidopsis and other plant species, mice, and humans.
The program is administered by the Department
of Molecular Genetics and Cell Biology and draws
its internationally distinguished faculty from that department as
well as from a number of others. At a broad level, the research
programs of this faculty seek to reveal the very basic molecular
mechanisms underlying biological phenomena in a cellular context.
Major research foci include the biogenesis of cellular organelles;
the assembly and organization of cellular structures; the coordination,
regulation and four dimensional orchestration of the cell division
cycle; the molecular basis of gene expression and regulation; cellular
and molecular aspects of chromosome recombination and transmission;
molecular and cellular mechanisms of metazoan development; mechanisms
of cell-cell interaction in fertilization, development and disease;
and how cells sense and respond to signals. Students trained in
the program are highly competitive for top postdoctoral positions
and go on to influential careers in basic academic, biomedical,
or industrial research.
See also:
•
Molecular Biosciences (official web site of the PhD Program)
• Admission
to Graduate Studies in the Molecular Biosciences
• Department of Molecular Genetics
and Cell Biology
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