Singh Group

Complete Bibliography

1. Scott, E.W., Simon, M.C., Anastasi, J. and Singh, H. (1994) Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265:1573-1577. (PubMed)

2. Scott, E.W., Fisher, R.C., Olson, M.C., Kehrli, E.W., Simon, M.C. and Singh, H. (1997) PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6:437-447. (PubMed)

3. Brass, A.L., Zhu, A.Q. and Singh, H. (1999) Assembly requirements of PU.1-Pip (IRF-4) activator complexes: Inhibiting function in vivo using fused dimers. EMBO J. 18:977-991. (PubMed)

4. Singh, H., DeKoter, R.P. and Walsh, J.C. (1999) PU.1, a shared transcriptional regulator of lymphoid and myeloid cell fates. Cold Spring Harbor Symposia on Quantitative Biology, Vol. 64:13-20, Cold Spring Harbor Laboratory Press, NY. (PubMed)

5. DeKoter, R.P. and Singh, H. (2000) Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288:1439-1441. (PubMed)

6. DeKoter, R.P., Lee, H.-J. and Singh, H. (2002) PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 16:297-309. (PubMed)

7. Kosak, S.T., Skok, J.A., Medina, K.L, Riblet, R., Le Beau, M.M., Fisher, A.G. and Singh, H. (2002) Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development. Science 296:158-162. (PubMed)

8. Bertolino, E. and Singh, H. (2002) POU/TBP cooperativity: a mechanism for enhancer action from a distance. Molecular Cell 10:397-407. (PubMed)

9. Walsh, J.C., DeKoter, R.P., Lee, H.-J., Smith, E.D., Lancki, D.W., Gurish, M.F., Friend, D.S., Stevens, R.L., Anastasi, J. and Singh, H. (2002) Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity 17:665-676. (PubMed)

10. Escalante, C.R., Brass, A.L., Pongubala, J.M.R., Shatova, E., Singh, H. and Aggarwal, A.K. (2002) Crystal structure of PU.1/IRF-4/DNA ternary complex. Molecular Cell 10:1097-1105. (PubMed)

11. Lu, R., Medina, K.L., Lancki, D.W. and Singh, H. (2003) IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 17:1703-1708. (PubMed)

12. Dahl, R., Walsh, J.C., Lancki, D., Laslo, P., Iye, S.R., Singh, H. and Simon, M.C. (2003) Regulation of macrophage and neutrophil cell fates by the PU.1 to C/EBPalpha ratio and G-CSF. Nature Imm. 4:1029-1036. (PubMed)

13. Medina, K.L., Pongubala, J.M., Reddy, K.L., Lancki, D.W., DeKoter, R., Kieslinger, M., Grosschedl, R., and Singh, H. (2004) Assembling a gene regulatory network for specification of the B cell fate. Developmental Cell 7:607-617. (PubMed)

14. Singh, H., Medina, K.L., and Pongubala, J. M.R. (2005) Contingent gene regulatory networks and B cell fate specification. Proc. Natl. Acad. Sci. USA. 102:4949-4953. (PubMed)

15. Bertolino, E., Reddy, K., Medina, K.L., Parganas, E., Ihle, J. and Singh, H. (2005) Regulation of IL-7 dependent immunoglobulin heavy-chain gene rearrangements by transcription factor Stat5. Nature Imm. 6:836-843 (PubMed)

16. Laslo, P., Spooner, C.J., Warmflash, A., Lancki, D., Lee, H-J., Sciammas, R., Gantner, B., Dinner, A. and Singh, H. (2006) Multilineage Transcriptional Priming and Determination of Alternate Hematopoietic Cell Fates. Cell 126:755-766. (PubMed)

17. Sciammas R., Shaffer A.L., Schatz J.H., Zhao H., Staudt L.M. and Singh H. (2006) Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 25:225-236. (PubMed)

18. Singh H. and Sciammas, R. (2006) Shedding B Cell Identity. Immunity 24:239–247. (PubMed)

19. Gantner, B and Singh, H. (2007) Immunology. Short-term memory. Nature 447:916-917. (PubMed)

20. Littman, DR and Singh H. (2007) Immunology. Asymmetry and immune memory. Science 315(5819):1673-4. (PubMed)

21. Singh, H. (2007) Shaping a helper T cell identity. Nature Immunology 8(2):119-20. (PubMed)

22. Pongubala, J.M., Northrup, D.L., Lancki, D.W., Medina, K.L., Treiber, T., Bertolino, E., Thomas, M., Allman, D. and Singh, H. (2008) Transcription Factor EBF Restricts Alternate Lineage Options and Promotes B Cell Fate Commitment Independently of Pax5. Nat Immunol 9:203-215. (PubMed)

23. Johnson, K., Hashimshony, T., Sawai, C.M., Pongubala J.M., Skok, J.A., Aifantis, I. and Singh, H. (2008) Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling. Immunity 28:335-345. (PubMed)

24. Reddy, K., Zullo, J., Bertolino, E., Singh, H. (2008) Transcriptional Repression Mediated by Repositioning of Genes to the Nuclear Lamina. Nature 452:243-247. (PubMed)

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